Over-the-Counter Anxiety Medication: Top-5 OTC Anxiety Medications At Walmart

Anxiety and stress have become increasingly prevalent in modern society, affecting individuals of all ages and backgrounds. The need for accessible and effective solutions to manage these conditions has led to the search for over-the-counter (OTC) anxiety medication.

Over-the-Counter Medicine for Anxiety and Stress

We have carefully evaluated various products available at Walmart to identify effective options for managing everyday anxiety. Our selection criteria include scientifically proven effective ingredients, safe dosages, affordability, positive customer feedback, and relevant certifications. However, it is important to note that supplements should only be considered as instant anxiety relief medication – when no other options are available. Additionally, if an individual is already taking medication, supplements should not be used. We strongly advise consulting with a physician before consuming any of the supplements described.

This article aims to explore the efficacy and availability of OTC anxiety meds, focusing on natural options that have gained popularity among consumers.

Understanding Over-the-Counter Anxiety Medication

Over-the-counter medications offer several advantages, such as convenience, affordability, and accessibility without the need for a prescription. When it comes to anxiety relief, there are various types of over-the-counter anxiety medication for adults.

However, it is crucial to consider certain factors when selecting an OTC medication, including the individual’s specific symptoms, potential side effects, and any interactions with other medications. Recommendations for the best OTC anxiety meds are based on effectiveness, affordability, and user satisfaction.

Our Top Of Best Over-The-Counter Anxiety Medication

Nature’s Bounty Anxiety and Stress Relief Supplement (Ashwagandha KSM-66)

Main Ingredients: Ashwagandha KSM-66 extract, supported by research verifying its anxiolytic effects.
Key Features: Ashwagandha is an herb with a long history of traditional use for stress and anxiety relief. Nature’s Bounty Anxiety and Stress Relief Supplement harnesses the benefits of Ashwagandha (specifically the KSM-66 extract) to provide a natural remedy for anxiety. This supplement offers a detailed product description, highlighting its ingredients and mechanisms of action. Exploring the benefits of Ashwagandha for anxiety relief, including its potential to reduce stress, promote relaxation, and support overall well-being, provides valuable insights for individuals seeking natural options.

Research: The study has demonstrated the effectiveness of Ashwagandha in reducing anxiety symptoms and improving overall well-being.

Package Contents: Each package contains 50 tablets.

Price: $10.98

Rating on Walmart’s Website: 4.4 stars out of 423 reviews

Nutricost 5-HTP Supplement

Main Ingredients: 5-Hydroxytryptophan (5-HTP), a naturally occurring amino acid that serves as a precursor to serotonin, a neurotransmitter involved in mood regulation.
Key Features: 5-Hydroxytryptophan (5-HTP) is a compound involved in mood regulation and the production of serotonin. Nutricost 5-HTP 100 mg Supplement provides a detailed product description, including information on its dosage and formulation. This section explores the efficacy of 5-HTP in managing anxiety and stress by supporting serotonin levels. User feedback and reviews of Nutricost 5-HTP on Walmart provide valuable insights into the experiences of individuals who have used this supplement for anxiety relief.

Research: Scientific studies have shown that 5-HTP supplementation can increase serotonin levels in the brain, leading to improvements in anxiety symptoms and overall mood.

Package Contents: The supplement is available in a 240-capsule package, offering an ample supply for extended use.

Price: $18.95

Rating on Walmart’s Website: 4 stars out of 146 reviews

Nature’s Way CalmAid Lavender Supplement

Main Ingredients: Lavender oil, derived from the flowers of Lavandula angustifolia, is known for its calming and soothing properties.

Key Features: Lavender has a rich history of use as a calming agent, known for its pleasant aroma and soothing properties. Nature’s Way CalmAid Non-Drowsy Lavender Supplement harnesses the benefits of lavender to reduce tension and stress. This section delves into the historical use of lavender and its potential as an effective natural remedy for anxiety. Clinical studies supporting the effectiveness of lavender for reducing tension and stress further strengthen its credibility as an OTC option. User experiences and reviews of Nature’s Way CalmAid provide additional insights into the effectiveness of this lavender supplement.

Research: Clinical studies have demonstrated the anxiolytic effects of lavender, including its ability to reduce tension, promote relaxation, and improve overall well-being.

Package Contents: the supplement is available in a package containing 30 softgels for daily use.

Price: $19.94

Rating on Walmart’s Website: 4.5 stars out of 100 reviews

Natural Rhythm Triple Calm Magnesium Supplement

Main Ingredients: Magnesium in the forms of taurate, glycinate, and malate, essential minerals known for their relaxation and stress-reducing properties.

Key Features: Magnesium plays a crucial role in relaxation and stress reduction within the body. Natural Rhythm Triple Calm Magnesium Supplement offers a detailed product description, highlighting the different forms of magnesium (taurate, glycinate, and malate) present in the supplement and their specific benefits. This section explores the benefits of magnesium for anxiety relief, including its potential to promote relaxation, improve sleep quality, and alleviate stress. User testimonials and reviews of Natural Rhythm Triple Calm on Walmart provide real-life experiences of individuals who have used this magnesium supplement for anxiety management.

Research: Study have shown that magnesium supplementation can promote relaxation, reduce anxiety symptoms, and support a sense of calmness.

Package Contents: The supplement comes in a package containing 120 capsules to support daily use.

Price: $21.97

Rating on Walmart’s Website: 4.4 stars out of 1158 reviews

OLLY Goodbye Stress Gummies

Main Ingredients: GABA (Gamma-Aminobutyric Acid) and L-Theanine, naturally occurring compounds known for their anxiety-reducing and stress-relieving properties.

Key Features: OLLY Goodbye Stress Gummies provide a convenient and tasty option for anxiety management. These gummies contain key ingredients such as GABA (gamma-aminobutyric acid) and L-Theanine, known for their potential in reducing anxiety and promoting relaxation. This section introduces OLLY Goodbye Stress Gummies and provides a detailed product description. The effectiveness of GABA and L-Theanine in anxiety management is explored, highlighting their mechanisms of action. Customer reviews and experiences with OLLY Goodbye Stress Gummies provide valuable insights into the satisfaction and effectiveness of this OTC option.

Research: Studies have demonstrated that GABA and L-Theanine can promote relaxation, reduce stress, and support a calm state of mind.

Package Contents: The gummies are available in a package containing 42 gummies for daily use.

Price: $12.88

Rating on Walmart’s Website: 4.3 stars out of 1256 reviews

The bonus option in this list is CBD. We have reviewed this option in a separate article.

What are the risks of using supplements?

It’s important to know the potential risks of using supplements for anxiety relief. Even though natural supplements might seem safe, they can still have negative effects if not used correctly or when combined with certain medications. Taking too much or mixing supplements can cause problems like trouble breathing, difficulty thinking clearly, and even harm to the liver.

For instance, if someone takes a popular natural supplement called 5-HTP for anxiety while also taking medications that increase serotonin levels, like selective serotonin reuptake inhibitors (SSRIs), they could develop a serious condition called serotonin syndrome. This condition can cause changes in mood, stiff muscles, fever, irregular heartbeat, and high blood pressure.

Although vitamins and minerals are generally safer than herbal supplements, it’s still important to talk to a healthcare provider before using any over-the-counter medicine for anxiety and stress. They can help make sure you use them safely and appropriately.

Can using OTC Anxiety Medication Replace Traditional Therapy?

While OTC anxiety relief supplements can offer temporary relief from symptoms, they shouldn’t be seen as a replacement for traditional therapy. Traditional therapy, like cognitive-behavioral therapy (CBT), is important for understanding the root causes of anxiety and developing helpful ways to cope with it. Therapy helps people learn about their thoughts and behaviors, find strategies to manage anxiety, and develop long-term skills for overall mental well-being.

Over-the-counter anxiety medication can be a helpful addition to therapy, but they shouldn’t be relied on as the main treatment for anxiety. It’s best to take a comprehensive approach that combines therapy, medication prescribed by a healthcare professional if necessary, and lifestyle changes.

Before adding any supplements to an anxiety treatment plan, it’s crucial to consult with a doctor or mental health professional. They can offer personalized advice, check for potential interactions with other medications, and help choose the most suitable and effective treatment for each person’s specific needs.


In conclusion, over-the-counter anxiety medications offer accessible options for individuals seeking relief from anxiety and stress. This article has explored natural OTC options, including Nature’s Bounty Anxiety and Stress Relief Supplement (Ashwagandha KSM-66), Nutricost 5-HTP Supplement, Nature’s Way CalmAid Lavender Supplement, Natural Rhythm Triple Calm Magnesium Supplement, and OLLY Goodbye Stress Gummies.

These products harness the benefits of natural ingredients to provide anxiety relief. However, it is important to consult healthcare professionals for personalized advice and to consider holistic approaches to managing anxiety and stress, such as therapy, lifestyle changes, and self-care practices. By considering these options, individuals can make informed choices in their journey toward better mental well-being.